Useful Websites for the Mouse Pathologist
This page aims at providing the mouse pathologists and scientists using Genetically Engineered Mice as models with useful websites ressources
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| Jackson Lab |
Almost everything about genetics
mutants, breeding etc |
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MGI, Mouse Genome
Informatics |
Integrated access to data on
the genetics, genomics, and biology
of the laboratory mouse. |
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MGI, mouse nomenclature
home page |
Rules of official names for mouse
genes, alleles, Mutations & strains |
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| Lee Silver's Mouse genetics |
Web version of the from L. Silver |
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| ENSEMBL |
Exploration of the mouse genome
(evaluation, annotation) |
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EULEP/EUropean Late Effects
Project |
Necropsy protocol & large photographs |
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| Virtual Mouse Necropsy, NIAID, |
Detailed necropsy protocol with drawings |
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UC Davis Center for Comparative
Medicine Mouse Virtual Necropsy
(not the same!) |
Interactive necropsy protocol for adult mice |
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EMPReSS/European Mouse
Phenotyping Resource of
Standardised Screens |
Standard Operating Procedures for clinical functional & morphological evaluation |
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RENI/Registry Nomenclature
Information System |
Well-illustrated trimming guidelines
mouse & rat, Excellent, links to publications |
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Index >Phenotyping > Histological techniques: |
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| University of Utah |
Histology Procedures Manual
Histological techniques (fixation, staining)
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| University of Bristol,
Veterinary Histopathology Department
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Histological staining techniques with illustrations
Excellent website
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| DAKO Handbook |
Immunohistochemical Staining Methods Educational Guide, 4th Edition |
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| Immunoportal |
Clearinghouse for IHC, ISH protocols
Image gallery
Searchable database of reagents suppliers, forums for trouble-shooting
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| University of Bristol |
Histological techniques, simple |
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| Laboratory of Experimental Pathology NIEHS / National Institute of Environmental Health Sciences |
Searchable database with detailed protocols & images for dozen of antigens
rodent & human tissues with illustrations |
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| Mouse Tumor Biology - IHC
Jackson Laboratory
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Alphabetical list of antibodies & labeling conditions tested on mouse tissues with illustrations |
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NCI / National Cancer Institute
LASP / Laboratory Animal Sciences Program
Murine IHC database
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Searchable database for optimized labeling on mouse tissues |
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| Columbia University |
Technical information, images |
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| Mutant Mouse Pathology Laboratory |
University of California, Davis, USA |
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| GEM Phenotyping Core Facility |
University of Cornell, USA |
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| JHU's Phenotyping Core |
John Hopkins Medicine, Maryland, USA |
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| Mouse Research Pathology |
Yale University, USA |
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| Mouse Phenotyping Shared Resource |
Ohio State University, USA |
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| ULAM/Unit for laboratory Animal Medicine |
University of Michigan, USA |
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| RADIL/Research Animal Diagnostic Laboratory |
University of Missouri, USA |
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| German Mouse Clinic |
Germany |
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| Institut Clinique de la Souris |
France |
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| MRC / Medical research Council
Mammalian genetics unit
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Harwell, UK |
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| Wellcome Trust Sanger Centre |
Cambridge, UK |
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| IMSR / International Mouse Strain Resource |
Global searchable catalog of mouse strain resources worldwide,
inbred, mutant, and genetically engineered mice
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| Deltagen & Lexicon Knock-out database, Trans NIH initiative, USA |
Searchable database with phenotypic data in different repositories |
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| JMSR / Japan Mouse Strain Resource |
Searchable database within 7 repositories
More than 2100 strains on the list
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| ILAR / Institute for Laboratory Animal research |
Search engine for animal models |
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| Phenome database, Jackson Laboratory, USA |
Searchable database on phenotype & genotype |
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| Frontiers in Bioscience |
Searchable database with phenotype datasheets |
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| MUGEN / Mutant Mouse Models of Human Immunological Disease Network |
Search engine for models of human immunological diseases |
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| Index >Searching for my mouse > Academic resources & repositories: |
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| Australian Phenomics Facility |
Repository of mouse strains, cryoarchived or live |
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| CARD R / BASE / Center for Animal Resource & Development, Japan |
International repository & distribution center for genetically engineered mice |
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| CMHD / Centre For Modelling Human Diseases, Canada |
ENU mutagenesis & gene trapping, collection of mutants with cardiovascular, hematopoietic, neurological & skeletal diseases |
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| CMMR / Canadian Mouse Mutant Repository |
Central repository of cryopreserved ES cells, spermatozoa, ova, embryos, and tissue DNA
Collection of somatic tissue from mouse models (fixed, embedded, glass / slide mounted).
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| EMMA- / European Mouse Mutant Archive |
Consortium, repository for mutant, transgenic, knock-out & other lines |
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| Centre for Molecular Medicine and Therapeutics Child & Family Research Institute, Canada |
Repository of mouse strains, cryoarchived or live |
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| MGU / Mouse Genetics Unit
MRC Harwell, UK
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Frozen Embryos & Sperm Archive, mutagenesis program |
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| The Center for New Mouse Models of Heart, Lung, Blood & Sleep Disorders Jackson Laboratory, USA |
Characterization of 40 inbred strains & ENU mutagenesis in different syndromes |
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| IMR / Induced Mutant Resource / Jackson Laboratory, USA |
Repository of mutant mice, 400 currently available |
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| MMHCC / Mouse Models of Human Cancers Consortium, NCI National Cancer Institute, USA |
Repository of cancer models, more than 100 strains (cryoarchived or live) |
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| MMRRC / Mouse Mutant Regional Resource Center Consortium |
Repository of mouse stocks & ES cell line collections shared by 4 partners |
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| Mouse TransGenics Consortium for Functional Glycomics,TSRI, USA |
Functional glycomics research |
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| National Institute of Genetics, Mammalian Genetics Laboratory, Japan |
Repository, more than 180 strains (inbred, mutant, congenic, transgenic) |
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| Neuromice, USA |
Consortium, 3 NIH facilities including TMGC
Development & distribution of neurological mutants
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| ORNL / Oak Ridge National Laboratory, USA |
Large collection of mouse stocks, mutations induced by radiations or chemicals |
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| RIKEN Institute Bioresource Center, Japan |
Mouse knockout database, ES cells clones from C57BL/6 & 129 gene trap libraries, More than 1,000 established mouse KO |
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| TIGM / Texas Institute for Genomic Medicine, USA |
Mouse knockout database, ES cells clones from C57BL/6 & 129 gene trap libraries, More than 1,000 established mouse KO |
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| Pathbase |
Searchable archive of pathology images |
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| MMHCC / Mouse Models of human Cancer Consortium |
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| emice: |
Organ mouse models overview |
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| caMOD |
Cancer models database |
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| caIMAGE |
Cancer image database |
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| UC Davis Center for Comparative Medicine / The visible mouse project |
Comparative anatomy & histology |
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| UC Davis Center for Comparative Medicine / Image archive |
Virtual slides, normal histology & tumors |
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| MTB / Mouse Tumor Biology Database |
Mouse models & human Searchable database, focusing on the biology of induced & inherited tumors |
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| Mammalian phenotype browser |
Links to many websites about cancer biology Searchable, hierarchical list of phenotypes |
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| NIAID / National Institute Allergic & Infectious Diseases National institute of Health |
Several links about pathology of GEMS |
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